Watch Carefully (1)norethindrone acetate decreases effects of liraglutide by pharmacodynamic antagonism. Use Caution/Watch. Oral contraceptives could lower hypoglycemic effects of antidiabetics by impairing glucose tolerance. Keep track of for glycemic control in diabetic clients.
Overdoses have already been reported in medical trials and publish-promoting usage of liraglutide. Outcomes have incorporated significant nausea, critical vomiting and significant hypoglycemia.
you or any of Your loved ones have at any time had a form of thyroid cancer identified as medullary thryroid carcinoma (MTC) or Should you have an endocrine technique issue termed Many Endocrine Neoplasia syndrome style two (Males 2).
Observe patients very carefully for indications and symptoms of pancreatitis (persistent severe abdominal soreness, occasionally radiating for the back again with or without the need of vomiting). If pancreatitis is suspected, discontinue Saxenda® instantly and when pancreatitis is verified, do not restart
Liraglutide can slow down the speed at which your abdomen empties, which could impact how nicely oral drugs are absorbed.
Lacking observations had been imputed with the placebo arm based on a jump to reference numerous (x100) imputation tactic.
perindopril raises consequences of liraglutide by not known system. Use Caution/Watch. ACE inhibitors might improve hypoglycemic result. Keep track of glycemic Manage Specifically in the course of the 1st month of treatment by having an ACE inhibitor. .
You’ll learn the way to give you a every day injection subcutaneously (beneath the pores and skin). Attach a new pen needle just before Each individual dose and in no way share your pen with everyone else. Pen needles are generally dispensed or marketed separately.
Hypoglycemia: Grownup individuals with style 2 diabetes on an insulin secretagogue (eg, a sulfonylurea) or insulin can have an elevated threat of hypoglycemia, together with extreme hypoglycemia with utilization of Saxenda®.
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The cumulative frequency distributions of improve in system pounds from baseline to week fifty six are demonstrated in Determine two for Scientific tests one and 2. One way to interpret this determine is to pick a change in body weight of fascination about the horizontal axis and Notice the corresponding proportions of individuals (vertical axis) in Every cure group who achieved not less than that degree of weight-loss.
By way of example, after you inject a dose in the upper arm, use a different section of your respective upper arm the following day or swap on your abdomen or thigh as an alternative. Utilizing the identical injection website repeatedly could lead to pores and skin problems, like a lump underneath the skin. For stage-by-move directions on how to inject Saxenda, look into the instructions for use.
ethinylestradiol decreases consequences of liraglutide by pharmacodynamic antagonism. Use Caution/Check. Oral contraceptives may possibly lower hypoglycemic results of antidiabetics by impairing glucose tolerance. Check for glycemic Regulate in diabetic sufferers.
There happen to be postmarketing experiences of more info acute renal failure and worsening of Long-term renal failure with liraglutide, which may sometimes involve hemodialysis; use with caution in these people